Abstract
A new megastimane sesquiterpenoid, cassianol A (1), and five known analogues (2–6) were isolated from the leaves extract of Cinnamomum cassia. Their structures were elucidated by extensive spectroscopic methods and single-crystal X-ray diffraction analyses. All the isolates were isolated from C. cassia for the first time. The anti-inflammatory activities of compounds 1–6 were evaluated against nitric oxide (NO) production in LPS-induced RAW 264.7 mouse macrophages.
Graphical Abstract
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Acknowledgments
We are grateful to Dr. C. Zhang at Huazhong University of Science and Technology for the authentication of this plant material. We thank the Analytical and Testing Centre at HUST for HRESIMS and crystallographic data collection.
Disclosure statement
No potential conflict of interest was reported by the authors.