Abstract
Five new fatty acids with a terminal 3-oxo-cyclopentene ring, cyclopentenone acids A–E (1–5), were isolated from the ethanol extract of the seeds of Hydnocarpus anthelminthica. The structures of these compounds were elucidated on the basis of their spectroscopic data and chemical evidence. Compounds 1-3 were evaluated for their anti-inflammatory activity based on the inhibition of NO production in microglial BV2 cells, and all of them showed weak anti-inflammatory activities.
Acknowledgments
The authors are grateful to the Department of Instrumental Analysis at our institute for the spectroscopic measurements.
Disclosure statement
No potential conflict of interest was reported by the authors.