Minor monoterpene derivatives from an aqueous extract of the hook-bearing stem of Uncaria rhynchophylla

Abstract

Seven new minor monoterpene derivatives (1–7), together with six known analogues, were isolated from an aqueous decoction of the hook-bearing stems of Uncaria rhynchophylla (Gou-teng). Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations, of which 1 was confirmed by single crystal X-ray diffraction.

Graphical Abstract

Keywords:

• Rubiaceae
• Uncaria rhynchophylla
• monoterpene derivatives
• uncariridins A–G

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Financial support from the National Natural Sciences Foundation of China (grant nos. 81630094 and 81730093) and CAMS Innovation Fund for Medical Science 2021-I2M-1-028 is acknowledged.