Abstract
Cynanotophyllosides E-F, two new minor pregnane glycosides were isolated from the antidepressant active fraction of cultivated Cynanchum otophyllum, and their structures were determined as 12-O-vanilloyl-deacetylmetaplexigenin 3-O--D-glucopyranosyl-(1→4)-
-D-glucopyranosyl-(1→4)-
-D-cymaropyranosyl-(1→4)-
-D-oleandropyranosyl-(1→4)-
-D-digitoxopyranoside, and 12-O-nicotinoyl-deacetylmetaplexigenin 3-O-
-D-glucopyranosyl-(1→4)-
-D-glucopyranosyl-(1→4)-
-D-cymaropyranosyl-(1→4)-
-D-oleandropyranosyl-(1→4)-
-D-cymaropyranoside respectively, with the combination of spectroscopic and chemical analysis.
Acknowledgments
The authors are grateful to Professor Chong-Ren Yang (Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China) for supplying the 2-deoxysugar samples and Prof. Li-Chun Yuan (the Institute of Alpine Economic Plant in Yunnan Academy of Agricultural Sciences, Lijiang, China) for supplying and identifying the plant material.
Disclosure statement
The authors report no conflicts of interest.