Two new bis-diterpenoid alkaloids from Aconitum weixiense

Abstract

Further investigation on the roots of Aconitum weixiense led to the isolation of two new bis-diterpenoid alkaloids, named as weisaconitines E and F (1–2), which were elucidated by IR, HR-ESI-MS, 1D- and 2D-NMR analyses. Their structures are characterized as denudatine-atisine-type bis-diterpenoid alkaloids.

Graphical Abstract

Keywords:

• Ranunculaceae
• Aconitum weixiense
• bis-diterpenoid alkaloids
• weisaconitines E and F

Acknowledgments

The authors are grateful to the staff of analytical group at the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences for the spectral data.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was financially supported by the National Natural Science Foundation of China (No. 31960096).