Abstract
Two new alkaloids, spongimides A (1) and B (2), along with five known ones (3–7), were isolated from the marine sponge Spongia sp. The structures of 1 and 2 were determined by the spectroscopic methods (UV, IR, MS, and NMR) and X-ray diffraction analysis. Compounds 1, 3, and 4 were the first examples of 2,4-imidazolidinediones isolated from this genus. In addition, the cytotoxic and antibacterial activities of compounds 1 and 2 were also evaluated.
![](/cms/asset/3f9668e4-5475-4c43-b05d-f2f312c87ecd/ganp_a_2197227_uf0001_c.jpg)
Disclosure statement
No potential conflict of interest was reported by the authors.