Four new triterpene saponins from the seeds of Aesculus Chinensis

Abstract

Two pairs of new geometrically isomeric triterpenoid saponins were isolated from the seeds of Aesculus chinensis and characterized as 28-acetyl-21-tigloylprotoaescigenin 3-O-[β-D-xylopyranosyl (1→2)] [β-D-glucopyranosyl (1→4)] [β-D-glucopyranosiduronic acid (isoescin IIa, 1) and 28-acetyl-21-angeloylprotoaescigenin 3-O-[β-D-xylopyranosyl (1→2)] [β-D-glucopyranosyl (1→4)] β-D-glucopyranosiduronic acid (isoescin IIb, 2); 28-acetyl-21-tigloylbarringtogenol C 3-O-[β-D-galactopyranosyl (1→2)] [β-D-glucopyranosyl (1→4)] β-D-glucopyranosiduronic acid (isoescin IIIa, 3) and 28-acetyl-21-angeloylbarringtogenol C 3-O-[β-D-galactopyranosyl (1→2)] [β-D-glucopyranosyl (1→4)] β-D-glucopyranosiduronic acid (isoescin IIIb, 4). Their structures were established on the basis of spectroscopic and chemical evidence.

Keywords:

• Triterpenoid glycosides
• Isoescins IIa, IIb, IIIa, and IIIb

Acknowledgements

This project was financially supported by the National Natural Science Foundation of the PR China (29972004).