A new triterpenoid from Entodon okamurae broth

Abstract

One new triterpenoid, entokamurol (1), was isolated from Entodon okamurae Broth, together with other nine compounds, namely dryocrassol (2), chrysophamol (3), physcion (4), 10-nonacosamnol (5), n-hexadecanol (6), phthalic acid isodibutyl ester (7), curcumol (8), β-sitosterol (9) and daucosterol (10). Their structures were elucidated on the basis of extensive NMR (DEPT, DQF-COSY, HMQC, HMBC and NOESY), IR and MS studies. All the compounds were isolated and identified from the genus of Entodon for the first time, and it is also the first report of a guaiane-type sesquiterpenoid and compounds with anthraquinone skeleton in mosses.

Keywords:

• Broth
• Entokamurol
• Triterpenoid
• Sesquiterpenoid
• Anthraquinone

Acknowledgements

This research was financially supported by the National Natural Science Foundation of China (No. 39600182). We acknowledge Dr Xue-sun Wen for identification of the plant species and the Central Laboratory in the School of Pharmacy for help in recording IR spectra. MS and NMR spectra were recorded by the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.