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Journal of Asian Natural Products Research Volume 6, 2004 - Issue 1
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Original Articles

Structural elucidation of fritillahupehin from bulbs of fritillaria hupehensis Hsiao et K.C. Hsia

Yong-Hui Zhang Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, ChinaCorrespondence[email protected]
,
Han-Li Ruan Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China
,
Hui-fang pi Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China
,
Ji-Zhou Wu Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, China
,
Han-Dong Sun Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, China
&
Tetsuro Fujita Faculty of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-01, Japan
Pages 29-34 | Received 06 Jan 2003, Accepted 02 Aug 2003, Published online: 15 Aug 2006
 
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Abstract

A novel diterpenoid ester, fritillahupehin (1) and three known fatty acids, palmitic acid (2), lignoceric acid (3) and azelaric acid (4), have been isolated from the bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16β-yl lignocerate by means of spectroscopic and chemical evidence. Compounds 2–4 were isolated from Fritillaria sp. for the first time.

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