Cycloartane-type triterpenoids from Sphaerophysa salsula

Abstract

Four novel cycloartanes, named sphaerophysone A (1), B (2), C (3) and D (4), were isolated from the ethanol extract of Sphaerophysa salsula (Pall.) DC. The structures were elucidated on the basis of spectral evidence, and the stereochemistry of compound 1 was defined by X-ray crystallographic analysis. Sphaerophysone B (2) may be an artifact formed in the isolation procedure.

Keywords:

• Leguminosae
• Sphaerophysa salsula
• Whole herbs
• Cycloartane
• Sphaerophysone A–D

Acknowledgements

Thanks are due to the Analytical Center of Shenyang Pharmaceutical University for measuring NMR, EIMS, FABMS and UV spectra.

Notes

Crystallographic data for the structure reported in this paper have been deposited with the Cambridge Crystallographic Data Centre. Copies of the data can be obtained free of charge, on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: [phone]) or e-mail: [email protected]).