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Abstract
A phytochemical investigation of the bark of Erythrophleum fordii furnished six compounds, of which one is a new diterpenoid glucopyranoside, named 15Z-[dodecahydro-18-hydroxymethyl-17,19,20-trimethyl-15(1H)-phenanthrenylidene]-acetic acid-16-O-β-d-glucopyranoside (1). Five known compounds were identified as (+)-taxifolin (2), (−)-robinetinidol (3), palmaitic acid (4), β-sitosterol (5) and baucosteyl (6), and were all isolated from the species for the first time. The structure of the new compound was elucidated on the basis of spectroscopic analyses and chemical methods.
Acknowledgements
This project was supported by the National Natural Science Foundation of China (No. 20272084) and the National Key Basic R&D program (973, No. G1998-051120). We are grateful to the department of medicinal analysis of the Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences for performing ESI-MS, NMR, IR and X-ray diffraction experiments, and thank the department of pharmacology, in our Institute, for cytotoxicity testing.