Note: A novel cyanogenic glycoside from Semiaquilegia adoxoides

Abstract

Phytochemical investigation of Semiaquilegia adoxoides was initiated in view of its common usage in traditional Chinese medicine and the scarcity of previous phytochemical studies. Fractionation of an ethanol extract from the roots of this plant led to the isolation and identification of a novel cyanogenic glycoside, 2-(β-d-glucopyranosyloxy)-4-hydroxybenzeneacetonitrile (1). The structure of 1 was elucidated on the basis of IR, FAB-MS, 1D and 2D NMR spectral analysis.

Keywords:

• 2-(β-d-Glucopyranosyloxy)-4-hydroxybenzeneacetonitrile
• Semiaquilegia adoxoides
• Cyanogenic glycoside

Acknowledgements

The authors would like to acknowledge the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry for financial support.