Monoterpenoids and their glycosides from Winchia calophylla

Abstract

Three new monoterpenoid compounds have been isolated from extracts of the stem barks of Winchia calophylla A. DC. The new compounds include two cyclo-diglycosides, wincaloside A (2) and wincaloside B (3), and a derivative of tetrahydroxycyclohexane-carboxylic acid, winchiepoxide (1). Their structures have been elucidated by spectroscopic and chemical methods.

Keywords:

• Winchia calophylla
• Apocynaceae
• Monoterpenoids
• Wincalosides A and B

Acknowledgements

This work was financially supported by the National Natural Science Foundation for Outstanding Young Scientists, to Professor Xiao-Jiang Hao (No.  39525025). The authors are grateful to Mr Y. N. He and Ms H. L. Liang, of the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring 2D and 1D NMR and HREIMS data, respectively.