Two new triterpenoid saponins from Ardisia crenata

Abstract

Two new triterpenoid saponins, ardisicrenoside K (1) and ardisicrenoside L (2), have been isolated from the roots of Ardisia crenata Sims. Their structures have been determined as 3β-O-{α-l-rhamnopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranosyl}-13β,28-epoxy-16-oxo-30,30-dimethoxyoleanane and 3β-O-{β-d-xylopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-α-l-arabinopyranosyl}-13β,28-epoxy-16α,20-dihydroxyoleanane by means of chemical evidences and spectral analysis. Their weak anti-fungal activity against the plant pathogenic fungus Pyricularia oryzae was evaluated in vitro.

Keywords:

• Ardisia crenata Sims
• Triterpenoid saponin
• Ardisicrenoside K
• Ardisicrenoside L
• Anti-fungal

Acknowledgements

The authors gratefully acknowledge Professor Qishi Sun of Department of Pharmacognosy, Shenyang Pharmaceutical University for identification of the plant. Thanks are also extended to the Shanghai Institute of Materia Medica of CAS for their assistance with HR-ESIMS.