Two new pregnane glycosides from soft coral Cladiellakrempfi

Abstract

Two new pregnane-type steroidal glycosides, pregna-5,20-dien-3-O-α-fucopyranoside (1) and pregna-20-en-3-O-α-fucopyranoiside (2), along with two known pregnane derivatives, were isolated from the soft coral Cladiella krempfi. Their structures were determined by spectroscopic data analysis.

Keywords:

• Soft coral
• Cladiella krempfi
• Pregna-5,20-dien-3-O-α-fucopyranoside
• Pregna-20-en-3-O-α-fucopyranoiside

Acknowledgements

This work is supported by grants from the National High Technology Development Project (863 project) (Nos. 2001AA620403, 2003AA620403 and 2002AA217081), NSFC (Nos. 40176038, 30171106) and the International Cooperation Projects of BMBF-CNCBD.