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Journal of Asian Natural Products Research Volume 8, 2006 - Issue 8
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Original Articles

Two new indole alkaloids from Naucleaofficinalis

W.-D. Xuan Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, China; PLA 411th Hospital, Shanghai, 200083, China
,
H.-S. Chen Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, ChinaCorrespondence[email protected]
,
J.-L. Du Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, China
,
S. Liang Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, China
,
T.-Z. Li Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, 200433, China
&
D.-G. Cai PLA 411th Hospital, Shanghai, 200083, China
Pages 719-722 | Received 09 Mar 2005, Accepted 23 Jun 2005, Published online: 06 Dec 2006
 
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Abstract

Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Nauclea officinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral data, especially 1D and 2D NMR experiments.

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