Alkaloids from Clematis manshurica Rupr.

Abstract

Three new alkaloids together with two known compounds have been isolated from the roots of Clematis manshurica. On the basis of their spectroscopic and chemical evidence, the new compounds were elucidated as methyl 7-ethoxy-3-indolecarbonate (2), methyl 7-O-α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranosyl 3-indolecarbonate (3) and α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranosyl 3-indolecarbonate (4).

Keywords:

• Clematis manshurica Rupr
• Alkaloid
• Methyl 7-ethoxy-3-indolecarbonate
• Methyl 7-O-α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranosyl 3-indolecarbonate
• α-l-Rhamnopyranos-yl-(1 → 6)-β-d-glucopyranosyl 3-indolecarbonate

Acknowledgements

We are thankful to Ministry of Science and Technology of PRC for their financial support. We are also grateful to members of the analytical centre of Peking University Health Science Centre. The HRFAB-MS were measured by the analyst of the Institute of Material Medica, Chinese Academy of Medical Science, Peking Union Medical College.