ent-Kaurenoids from the roots of Cacalia pilgeriana

Abstract

Two new ent-kaurenoids,19-acetoxyl-ent-3β,17-dihydroxykaur-15-ene (1), 19-acetoxyl-ent-3β-hydroxykaur-15-en-17-al (2), together with seven known ent-kaurenoids: ent-kaur-16-en-19-al (3), ent-kaur-16-en-19-oic acid (4), ent-kauran-16β,17-diol (5), ent-15β, 16β-epoxy-17-hydroxykauran-19-oic acid (6),19-acetyl-ent-3β-hydroxyl-kaur-16-ene (7), ent-3β,19-dihydroxykaur-16-ene (8), ent-17-hydroxykaur-15-ene (9), were isolated from Cacalia pilgeriana. Their structures were elucidated by spectroscopic methods including 2D NMR spectral analysis.

Keywords:

• Cacalia pilgeriana
• Compositae
• ent-Kaurenoid
• 19-acetoxyl-ent-3β,17-dihydroxykaur-15-ene,19-acetoxyl-ent-3β-hydroxykaur-15-en-17-al

Acknowledgements

This work was supported by the NSFC (No.20372029 and No.20021001) and by the Key Project of Chinese Ministry of Education (No. 104178).