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Original Articles

Total synthesis of natural product (R)-4-phenyl-2-O-[β-d-xylopyranosyl(1→6)-β-d-glucopyranosyl]butane and its epimer

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Pages 223-231 | Received 09 Nov 2004, Accepted 17 Jan 2005, Published online: 04 Mar 2011
 

Abstract

The new compound (R)-4-phenyl-2-O-[β-d-xylopyranosyl(1 → 6)-β-d-glucopyranosyl]butane (1) and its epimer (2), together with (R)-4-phenyl-2-O-β-d-glucopyranosyl butane (24) and (S)-4-phenyl-2-O-β-d-glucopyranosyl butane (25) were firstly synthesized from 4-phenylbutan-2-one and glucose. The absolute configuration of C-2 for 1 was confirmed as R. Their anti-tumour activities were evaluated.

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