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Journal of Asian Natural Products Research Volume 9, 2007 - Issue 7
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Original Articles

Immunosuppressive terpenes from Prinsepia utilis

YING-QIAN Xu School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China; The School of Chemical Engineering, Anshan University of Science & Technology, Liaoning Anshan, 114002, China
,
ZHI Yao Department of immunology, Tianjin Medical University, Tianjin, 300070, China
,
JUN-YI Hu The School of Chemical Engineering, Anshan University of Science & Technology, Liaoning Anshan, 114002, China
,
JIE Teng School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China
,
YOSHIHISA Takaishi Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1–78, Tokushima, 770-8505, Japan
&
HONG-QUAN Duan School of Pharmacy, Tianjin Medical University, Tianjin, 300070, ChinaCorrespondence[email protected]
Pages 637-642 | Received 16 Mar 2006, Accepted 24 Jun 2006, Published online: 04 Mar 2011
 
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Abstract

Two new hemiterpenes, utililactone (1) and epiutililactone (2), along with nine known compounds (3–11), were isolated from the leaves of Prinsepia utilis. Their structures were elucidated on the basis of spectroscopic data. The isolated compounds showed significant immunosuppressive activities.

Acknowledgements

The Project was sponsored by the Scientific Research Foundation of Tianjin Medical University.

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