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Journal of Asian Natural Products Research Volume 10, 2008 - Issue 2
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Original Articles

Chemical constituents of Nouelia insignis Franch

X.-Y. Hu Northwest Sci-Tech University of Agriculture and Forestry, Yangling, 712100, China
,
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China
,
Y.-Gang Luo Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China
,
Xiao-Zhen Chen Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China
,
Le Zhou Northwest Sci-Tech University of Agriculture and Forestry, Yangling, 712100, China
&
Guo-Lin Zhang Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, ChinaCorrespondence[email protected]
Pages 125-131 | Received 28 Aug 2008, Accepted 02 Jan 2007, Published online: 05 Feb 2008
 
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Abstract

Two new diterpenes and ent-15α-hydroxykaur-16-en-19-oic acid 11,12-acetonide (3), together with 23 known compounds were isolated from the dried aerial parts of Nouelia insignis Franch. The structures of new compounds were determined to be ent-14β,15α-dihydroxykaur-16-en-19-oic acid (1), ent-14β-hydroxy-15-oxokaur-16-en-19-oic acid (2) on the basis of spectral and chemical evidence. The structure of ent-11α,16α-epoxy-15α-hydroxy-16S-kaur-19-oic acid (4) was confirmed by X-ray crystallographic analysis.

Acknowledgements

The authors are grateful to Mr. Jian Gu at Chengdu Institute of Biology of the Chinese Academy of Sciences for collecting the plant material.

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