Three new triterpenoid saponins from the seeds of Aesculus turbinata

Abstract

Three new triterpenoid saponins, named isoescins VIIa (1), VIa (2), and VIIIa (3), were isolated from the seeds of Aesculus turbinata and identified by spectroscopic analysis and chemical hydrolysis. Their structures were established as 21β-O-tigloyl-28-O-acetylprotoaescigenin 3β-O-[β-d-galactopyranosyl(1 → 2)][β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIIa, 1), 21β-O-(2-methylbutyryl)-28-O-acetylprotoaescigenin 3β-O-[β-d-glucopyranosyl(1 → 2)] [β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIa, 2), and 21β-O-angeloyl-28-O-acetylbarringtogenol C 3β-O-[β-d-glucopyranosyl(1 → 2)] [β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIIIa, 3).

Keywords:

• Hippocastanaceae
• Aesculus turbinata
• isoescin VIa
• isoescin VIIa
• isoescin VIIIa

Acknowledgements

This work is supported by the National Natural Science Foundation of China (29972004).