Benzophenone C-glucosides from Polygala glomerata Lour

Abstract

Four new benzophenone C-glucosides, glomeratides A (1), B (2), C (3), and D (4), along with a known compound arrilanin G (5), have been isolated from the whole plant of Polygala glomerata Lour. Their structures were determined by extensive analyses of their spectral data. Compounds 1–5 showed hepatoprotective activities against d-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells.

Keywords:

• Polygala glomerata
• benzophenone
• C-glucosides
• hepatoprotective

Acknowledgements

The authors would like to thank the National Natural Science Foundations of China for the financial support (Nos. 20432030, 20372087).