Two new coumarins from Murraya paniculata

Abstract

Two new coumarins, murrmeranzin (1) and murralonginal (2), together with four known compounds minumicrolin (3), murrangatin (4), meranzin hydrate (5) and hainanmurpanin (6) have been isolated from the aerial parts of Murraya paniculata. The structures of these compounds were determined through spectral analysis. Minumicrolin (3) showed mild butyrylcholinesterase inhibition activity.

Keywords:

• Murraya paniculata
• Rutaceae
• minumicrolin
• butyrylcholinesterase inhibitor
• murrmeranzin
• murralonginal

Acknowledgements

This work has been accomplished by the financial grant provided by the Dean Faculty of Science, University of Karachi. We are also grateful to Professor Dr M. Iqbal Chaudhary _S.I.,T.I., Acting Director, HEJ Research Institute of Chemistry, I.C.C.S, University of Karachi, for providing spectroscopic facilities and for the determination of enzyme inhibition activity.