Two new triterpenoid saponins from the flowers and buds of Lonicera japonica

Abstract

Two new triterpenoid saponins, loniceroside D (1) and loniceroside E (2), were isolated from the dry flowers and buds of Lonicera japonica Thunb., along with seven known compounds, chlorogenic acid (3), sweroside (4), vogeloside (5), epi-vogeloside (6), loniceroside A (7), loniceroside B (8), and loniceroside C (9). Their structures were elucidated on the basis of spectroscopic data, physicochemical properties, and acid hydrolysis.

Keywords:

• Lonicera japonica Thunb.
• triterpenoid saponin
• loniceroside D
• loniceroside E

Acknowledgements

This project was supported by the National Natural Science Foundation of China (Grant No. 30672601). NMR spectra were measured by Institute of Materia Medica, Chinese Academy of Medical Sciences; Mass spectra were operated at the Center of Chemical Institution of Chinese Academy of Sciences and Academy of Military Medical sciences.