A new diterpenoid from the south China sea soft coral Lobophytum sp.

Abstract

A new cembrane-type diterpene, 11,12-epoxy-sarcophytoxide (1), along with five related diterpenoids (2, and 4–7), has been isolated from the soft coral Lobophytum sp. The structure of the new compound 1 was elucidated on the basis of detailed analysis of its spectroscopic data, and by comparing its NMR spectral data with those of the model compounds.

Keywords:

• soft coral
• Lobophytum sp
• cembranoid
• 11,12-epoxy-sarcophytoxide

Acknowledgements

This work was financially supported by the National Marine ‘863’ Project (nos. 2006AA09Z412 and 2007AA09Z447), the Natural Science Foundation of China (nos. 20572116, 30730108, 20721003), CAS Key Project (grant KSCX2-YW-R-18), and STCSM Projects (nos. 07XD14036 and 06DZ22028).