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Original Articles

Microbial transformation of alantolactone by Mucor polymorphosporus

, , , , &
Pages 933-937 | Received 18 Dec 2007, Accepted 03 May 2008, Published online: 11 Nov 2008
 

Abstract

Two new transformed sesquiterpenes of alantolactone by Mucor polymorphosporus were obtained. They were characterized as 3β-hydroxy-11βH-eudesm-5-en-8β,12-olide (2) and 3β,11α-dihydroxy-eudesm-5-en-8β,12-olide (3), on the basis of spectral methods including 2D NMR. And product 3 was an unusual hydroxylation derivative of alantolactone at C-11.

Acknowledgements

We thank the Youth Foundation (30701088) by National Natural Science Foundation of China and PHR (IHLB) for financial support.

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