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Journal of Asian Natural Products Research Volume 10, 2008 - Issue 11
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Original Articles

A new pregnane glycoside from Marsdenia roylei as potential antioxidant and antidyslipidemic agents

Arun Sethi Department of Chemistry, University of Lucknow, Lucknow, IndiaCorrespondence[email protected]
,
Sudha Paswan Department of Chemistry, University of Lucknow, Lucknow, India
,
Sanjay Srivastava Department of Applied Sciences, Institute of Engineering and Technology, Lucknow, India
,
Naveen Kumar Khare Department of Chemistry, University of Lucknow, Lucknow, India
,
Akriti Bhatia Department of Chemistry, University of Lucknow, Lucknow, India
,
Alok Kumar Department of Chemistry, Northern India Engineering College, Lucknow, India
,
Geetika Bhatia Division of Biochemistry, Central Drug Research Institute, Lucknow, India
,
Mohammad Mubin Khan Division of Biochemistry, Central Drug Research Institute, Lucknow, India
,
Ashok Kumar Khanna Division of Biochemistry, Central Drug Research Institute, Lucknow, India
&
Jitendra Kumar Saxena Division of Biochemistry, Central Drug Research Institute, Lucknow, India
 show all
Pages 1023-1028 | Received 11 Dec 2007, Accepted 08 May 2008, Published online: 22 Nov 2008
 
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Abstract

A new pregnane glycoside roylenine (1) was isolated from the CHCl3–EtOH (4:1) extract of Marsdenia roylei. Its structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (6) were evaluated for their antioxidant and antidyslipidemic activities.

Acknowledgements

The authors are grateful to the RSIC division of the Central Drug Research Institute, India, for the analytical data.

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