Syntheses of R-β-rutinosides by rutin-degrading reaction

Abstract

Rutinose and five R-β-rutinosides were obtained by means of rutin-degrading reaction in water or aqueous alcohol (ROH, R = methyl, ethyl, propyl, isopropyl, and benzyl) with rutin-degrading enzyme as catalyst and rutin as starting material in 84–94% yields, of which methyl-β-rutinoside, propyl-β-rutinoside, isopropyl-β-rutinoside, and benzyl-β-rutinoside are firstly reported in this paper. Based on spectral analysis, the structures of all products were elucidated.

Keywords:

• rutinoside
• rutin-degrading reaction
• rutinose
• rutin

Acknowledgements

We thank the National Science Foundation of China (30571402) for financial support to this research and Prof. Y. Chai in Northwest A&F University for friendly providing the plant material.