Two new lignans from Phyllanthus amarus

Abstract

Two new lignans, 3-(3,4-dimethoxy-benzyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl-methyl)-dihydrofuran-2-one (1) and 4-(3,4-dimethoxy-phenyl)-1-(7-methoxy-benzo[1,3]dioxol-5-yl)-2,3-bis-methoxymethyl-butan-1-ol (2), were isolated from the leaves of Phyllanthus amarus and their structures were established by spectral analysis. Additionally, eight known lignans were also isolated and characterized.

Keywords:

• Phyllanthus amarus
• Euphorbiaceae
• γ-butyrolide lactones
• lignans

Acknowledgements

The authors are thankful to the Director, CIMAP for his keen interest during the course of this work and the Council of Scientific and Industrial Research (CSIR) for providing financial support.