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Journal of Asian Natural Products Research Volume 12, 2010 - Issue 2
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Original Articles

Chemical constituents from the cell cultures of Saussurea involucrata

Ri-Dao Chen Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Biosynthesis of Natural Drugs, Ministry of Public Health & Key Laboratory of Bioactive Substances and Resources Utilization, Ministry of Education), Beijing, 100050, China; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, China
,
Jian-Hua Zou Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Biosynthesis of Natural Drugs, Ministry of Public Health & Key Laboratory of Bioactive Substances and Resources Utilization, Ministry of Education), Beijing, 100050, China
,
Jing-Ming Jia School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, 110016, ChinaCorrespondence[email protected]
&
Jun-Gui Dai Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (Key Laboratory of Biosynthesis of Natural Drugs, Ministry of Public Health & Key Laboratory of Bioactive Substances and Resources Utilization, Ministry of Education), Beijing, 100050, ChinaCorrespondence[email protected]
Pages 119-123 | Received 21 Sep 2009, Accepted 11 Nov 2009, Published online: 04 Feb 2010
 
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Abstract

The chemical constituents of the cell cultures of Saussurea involucrata were systematically investigated, thus a new eudesmane-type sesquiterpene together with 14 known compounds was isolated. Among them, syringin is the main compound with an isolated yield of 0.3%. The new compound was characterized as 11βH-2α-hydroxy-eudesman-4(15)-en-12,8β-olide (1) on the basis of extensive spectroscopic data.

Acknowledgements

The authors gratefully acknowledge the financial support for this work by Beijing Natural Science Foundation (Grant No. 7092070) and the Program for New Century Excellent Talents in University (Grant No. NCET-06-0155).

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