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Journal of Asian Natural Products Research Volume 12, 2010 - Issue 2
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Original Articles

Total synthesis of baicalein

Duo-Zhi Chen Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, China
,
Jian Yang Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, ChinaCorrespondence[email protected]
,
Bo Yang Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, China
,
Yuan-Shuang Wu Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, China
&
Ting Wu Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650224, China
Pages 124-128 | Received 26 Sep 2009, Accepted 23 Nov 2009, Published online: 04 Feb 2010
 
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Abstract

In this paper, a simple and novel synthesis of baicalein is described. This transformation features the novel synthesis of helilandin B and a different way to demethylate. The overall yield of 59% is acceptable.

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