FeCl₃Mediated Simple, Green, and Efficient Method for the One-Pot Synthesis of Pyrazine-based Polycyclic Aromatic Compounds under Mild Conditions

Abstract

Iron(III) trichloride-catalyzed reactions of 1,2-diamines and 1,2-diketones produce pyrazine-based polycyclic aromatic compounds in good to excellent yields. The reactions proceed with 20 mmol% catalyst in water under mild conditions.

Supplemental materials are available for this article. Go to the publisher's online edition of Polycyclic Aromatic Compounds to view the supplemental file.

Key Words:

• 1
• 2-diamine
• 1
• 2-diketone
• iron(III) trichloride
• polycyclic
• pyrazine
• water

Acknowledgments

The authors are grateful to the PNU for funding this work.