TiCl₄/nano Sawdust as a Biocatalyst for the Synthesis of Ethyl 2-Amino-5-Oxo-4H,5H-Pyrano[4,3-b]Pyran-3-Carboxylates

Abstract

TiCl₄/nano sawdust has been prepared from nano sawdust and TiCl₄ in chloroform as solvent. Then TiCl₄/nano sawdust has been applied as a catalyst for synthesis of pyrano [4,3-b] pyrans from the simple one-pot reaction between aryl aldehydes, ethyl 2-cyanoacetate and 4-hydroxy-6-methyl-2H-pyran-2-one. Cleanliness, good to excellent yields of products, simple methodology, and an eco-friendly catalyst are some advantages of this method.

Keywords:

• aryl aldehydes
• ethyl 2-cyanoacetate
• pyrano [43-b] pyrans
• TiCl₄/nano sawdust
• 4-hydroxy-6-methyl-2H-pyran-2-one