Abstract
A convenient synthesis of 2-substituted benzothiazoles and benzoxazoles from the reaction o-aminophenol or o-aminothiophenol with acyl chlorides or acid anhydrides has been accomplished. The various carboxylic acid derivatives were reacted with o-aminophenol or o-aminothiophenol in the presence of KF-Al2O3 as a base heterogeneous catalyst to form correspondence benzothiazoles and benzoxazoles in high yields, and the catalyst showed a good recyclability.
Acknowledgement
We gratefully acknowledge the support of this work by Shiraz university research council.
Disclosure statement
No potential conflict of interest was reported by the authors.