Green Synthesis of Novel Triflouromethyl-1H-Benzo[f]chromenes Using 2-Oxoimidazolidine-1,3-Disulfonic Acid

Abstract

2-Oxoimidazolidine-1,3-disulfonic acid is a recoverable catalyst for the synthesis of novel triflouromethyl-1H-benzo[f]chromene by the condensation of 2-naphthol, 4,4,4-trifluoro-1-phenyl-1,3-butanedione and different substituted benzaldehyde at room temperature in a one-pot procedure without additional organic solvents. Moreover, the catalyst could be easily recovered and recycled for five runs without significant loss of its catalytic activity. The structures of the synthesized triflouromethyl-1H-benzo[f]chromene compounds were confirmed by ¹H, ¹³C nuclear magnetic resonance and Fourier-transform infrared spectral data and elemental analyses.

Keywords:

• Benzo[f]chromenes
• green synthesis
• one-pot reaction
• solid acid

Disclosure statement

There is no conflict of interest.

Table 1. Comparison of different catalysts or media for the synthesis of phenyl(1-(p-tolyl)-3-(trifluoromethyl)-1H-benzo[f]chromen-2-yl)methanone (4a) at room temperature.

Table 2. Synthesis of triflouromethyl-1H-benzo[f]chromenes.

Additional information

Funding

Financial support by Rasht Branch, Islamic Azad University is gratefully acknowledged.