Abstract
Several new fused polycyclic 2,3-dihydro-thieno[2,3-b]quinolin-3-ol derivatives were synthesis through the un-catalyzed reaction of various 2-mercaptobenzoquinoline-3-carbaldehydes with 2-bromoacetophenones in CH2Cl2 at 80–90% yield. Besides, reaction of differently substituted 3-formyl-2-mercaptoquinolines and various 1,3-dicarbonyl compounds such as dimedone, ethyl acetoacetate and 1,3-indandione) in the presence of AlCl3 as an efficient catalyst in CH2Cl2 at room temperature gave different novel fused polyheterocycle derivatives depends on the selection of 1,3-dicarbonyl compounds, respectively.
Acknowledgment
We are thankful to Alzahra University and the Iran National Science Foundation (INSF) for the financial support.