Magnetically Recoverable Graphene-Based Nanoparticles for the One-Pot Synthesis of Acridine Derivatives under Solvent-Free Conditions

Abstract

Acridine derivatives were synthesized by reaction of dimedone, aromatic amines/ammonium acetate and various aromatic aldehydes in the presence of a new and green graphene oxide incorporated strontium magnetic nanocatalyst (MSrGO NCs) under solvent-free conditions. This methodology offers many advantages including operational simplicity, good to excellent yields (up to 97%), short reaction times, the remarkable magnetic property of the nanocomposite, and easy separation of the nanocatalyst from the reaction mixture by magnetic decantation and reused several times without significant loss of catalytic activity.

Keywords:

• Acridine
• graphene oxide
• heterogeneous catalyst
• magnetic nanocatalyst
• solvent-free

Acknowledgments

Authors would like to thank Iran's National Elites Foundation for the financial support and Tehran University of Medical Sciences for facilities and financial support.