Sulfated Copper Oxide Catalyzed One-Pot Synthesis of N-Fused Benzimidazolo/Benzothiazolo Pyrimidines

Abstract

A recyclable sulfated copper oxide catalyst in acetonitrile is effective for the synthesis of N-fused benzimidazolo/benzothiazolo pyrimidine derivatives by the reaction of 2-aminobenzimidazole/2-aminobenzothiazole, phenyl acetylene, and benzaldehydes. This method is a unified approach to assemble a wide variety of fused pyrmidines.

Keywords:

• Benzimidazoles
• benzothiazoles
• multicomponent reaction
• pyrimidines
• sulfated copper oxide

Disclosure statement

The authors declare no conflict of interest.

Additional information

Funding

S.J is thankful to Council of Scientific and Industrial Research (CSIR), New Delhi for providing Senior Research Fellowship (SRF) [Grants Reference no. 02(0172)/13/EMR-II, Dated: 21.10.2013].