Abstract
In this green procedure is described easy access to highly functionalized 2-amino-5,10-dioxo-4-aryl-5,10-dihydro-4H-benzo[g]chromene-3-carbonitriles using the reaction of aldehydes, 2-hydroxy-1,4-naphthoquinone and malononitrile in the presence of L-proline as an organocatalyst under reflux condition in ethanol. Also, some unprecedented of 2-amino-5,10-dioxo-4-aryl-5,10-dihydro-4H-benzo[g]chromene-3-carbonitriles were synthesized via this route. The chemical shift of NH2 in the new products was evaluated by 1HNMR technique in D2O and without D2O.