Preparation and Characterization of a Novel Magnetic Nano Catalyst for Synthesis and Antibacterial Activities of Novel Furan-2(5H)-Ones Derivatives

Abstract

Sulfamic acid 2-Aminobenzothiazole-6-carboxylic acid functionalized Fe₃O₄ nanoparticles as a novel organic-inorganic hybrid heterogeneous catalyst were manufactured and characterized by FT-IR, XRD, TGA, SEM, TEM, and VSM techniques. The catalytic activity of the magnetic catalyst was investigated through the one-pot synthesis of novel 3,4,5-trisubstituted furan-2(5H)-ones derivatives from aryl aldehydes, 4-amino pyridine, and dimethyl acetylenedicarboxylate. The structure of all the new synthesized derivatives was determined by FT-IR, ¹H-NMR, and ¹³C-NMR. The synthetic compounds exert moderate activity against both Gram-positive and Gram-negative bacteria and their effectiveness is higher against Bacillus subtilis. This green nano catalytic procedure has good reversibility and provides clean production in a short reaction time. These characters make the method practical and economical for researchers.

Keywords:

• Arylaldehydes
• 4-amino pyridine
• dimethylacetylenedicarboxylate
• novel furan
• nanoparticles

Acknowledgments

This research was supported by the ChiFeng Industry Vocational Technology College.

Disclosure statement

There are no conflicts of interest.