Degree Based Weighted Entropy Indices of Hyaluronic Acid-Curcumin Conjugates: an Anti-Tumor Drug

Abstract

The topological index is a molecular predictor that is commonly supported in the research of QSAR of pharmaceuticals to numerically quantify their molecular features. Theoretical and statistical study of drug-like compounds improves the drug design and finding work-flow by rationalizing lead detection, instant decision, and mechanism of action comprehension. Using molecular structure characterization and edge segmentation technique, we have computed degree-based entropy and edge weight-based entropy indices of hyaluronic acid-curcumin conjugate which is used as an anti-cancer drug.

Keywords:

• Quantitative structure-property relationship (QSPR)
• degree-based entropy
• edge weight-based entropy
• topological indices

Mathematics Subject Classification:

• 05C09
• 05C92
• 92E10

Disclosure statement

No potential conflict of interest was reported by the authors.