Na₂Ca(HPO₄)_2, an Efficient, Reusable Eco-Friendly Catalyst for the Synthesis of 1,8-Dioxo-Octahydroxanthenes and Biscoumarin Derivatives

Abstract

In this paper, Na₂Ca(HPO₄)₂ was used for the first time as a heterogeneous catalyst for efficient and green synthesis of 1,8-dioxo-octahydroxanthenes and biscoumarin derivatives. Under optimal conditions, the products were obtained with excellent yields in a short reaction time. This developed procedure has shown several advantages: avoiding toxic solvents, catalyst, simple handling, mild conditions, easy recovery, and catalyst reuse.

Na₂Ca(HPO₄)₂ as a heterogeneous catalyst guarantees an environmentally friendly process; it can be considered an alternative to the other previously reported synthesis methods.

Keywords:

• Na₂Ca(HPO₄)₂
• 1,8-dioxo-octahydroxanthenes
• biscoumarin
• heterogeneous catalyst
• environmentally friendly process

Disclosure statement

No potential conflict of interest was reported by the author(s).