Abstract
The zinc (II) complex supported on magnetic nanoparticles Fe3O4 as a novel and efficient magnetically recoverable catalyst (Fe3O4-Phenanthroline-Zn) was designed and characterized using the most common spectroscopic techniques including FT-IR spectroscopy, SEM, TEM, EDX, XRD, VSM, and ICP-OES. The Fe3O4-Phenantroline-Zn catalyst is shown to be efficient for the multicomponent synthesis of heterocycles including highly substituted piperidines and pyrano[2,3-d]pyrimidines. This system has many advantages, such as excellent level of reusability of magnetic catalysts, high yields, simplicity of separation of catalysts using an external magnet, environmental benignity and ease of handling. To the best of our knowledge, it is the first report on the utilization of zinc nanomagnetic catalyst for the multicomponent synthesis of highly substituted piperidines.
Graphical Abstract
Acknowledgement
This work was supported by the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia [Project No. GRANT721].
Disclosure statement
No potential conflict of interest was reported by the author(s).