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Research Articles

A Facile, One-pot, and Green Method for Synthesis of 2-Aryl-3-(Phenylamino)Dihydroquinazolin-4(1H)-One Derivatives Using Sodium Lauryl Sulfate (SLS) in Aqueous Media at the Room Temperature

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Pages 981-993 | Received 11 Aug 2022, Accepted 18 Feb 2023, Published online: 08 Mar 2023
 

Abstract

A facile, one-pot, and green method for synthesis of 2-aryl-3-(phenylamino)dihydroquinazolin-4(1H)-one derivatives using Sodium Lauryl Sulfate (SLS) in aqueous media at room temperature through a reaction between isatoic anhydride, phenylhydrazine, benzaldehyde derivatives in the presence of SLS. This one-pot protocol provides these valuable desired compounds under mild and green conditions with excellent efficiency by using simple available starting materials.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by University of Tehran.

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