Abstract
In this research the one-pot multicomponent reactions of cefixime (CFX), activated acetylenic compounds and alkyl bromids in water as solvent at room temperature in the presence of catalytic amounts of ZnO/Fe3O4@MWCNTs magnetic nanocomposites as catalyst was investigated which was produced new derivatives of pyrroles in good yields. In this research, the high performance of nanocatalyat ZnO/Fe3O4@MWCNTs magnetic nanocomposites was synthesized by using water extract of Petasits hybridus leaves, which was utilized in these reactions for many times to confirm the reusability of nanocatalyst. and utilized as an environmental-friendly adsorbent for cefixime (CFX) and amoxicillin (AMX) removal. The adsorption parameters, including the initial CFX and AMX concentration, contact time; solution pH, temperature, and adsorbent dosage were investigated. The adsorption kinetic and isotherm were well fitted by the pseudo second-order and Langmuir models, respectively. The short time of reaction, high yields of product and easy separation of catalyst and product are some advantages of this procedure.
Highlights
Green chemistry is the use of a set of principles to reduce or eliminate the use or generation of unsafe materials in the design, fabrication and applications of chemical products. Among solvents, water is a green solvents and very suitable for performing organic reaction.
The present procedure avoids the use of toxic solvent.
According to obtained results, the active carbon adsorbed the both of cefixime and amoxicillin but the zeolite didn’t adsorb the amoxicillin but adsorbed the high percentage of cefixime in the batch procedure.
Disclosure statement
No potential conflict of interest was reported by the author(s).