An Efficient Synthesis of 1, 3-Oxazine Derivatives Catalyzed under Ceric Ammonium Nitrate in an Aqueous Medium at Ambient Temperature

Abstract

We report that ceric ammonium nitrate mediated the synthesis of 1, 3-oxazine derivatives under the green method. In the reaction, 20 mol% catalysts are sufficient for the complete conversion of the reaction. The condensation reaction of β-naphthol with formaldehyde and primary amines those containing electron-donating as well as electron-withdrawing substituents under the aqueous reaction condition at ambient temperature in the presence of ceric ammonium nitrate has been developed as an efficient and eco-friendly precursor for the determination of 1, 3-oxazine derivatives. This approach has numerous benefits beyond conventional systems, notably ease of use, expense, reusability of the catalyst, and faster reaction times.

Keywords:

• Formaldehyde
• amines
• β-naphthol
• ceric ammonium nitrate
• solvent-free condition

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The authors Ashok Pise, Ajit Ingale, and Shripad M. Patil are thankful to Principal, Dada Patil Mahavidyalaya, Karjat-414401, Maharashtra (INDIA) for giving financial support for this research work.