Some Aspects of the Analysis of Biologically Active Organogermanium Substances

Abstract

An attempt of synthesis of information concerning organogermanium compounds has been accomplished. Organic germanium derivatives exhibit biological activity. This fact is very important for the whole ecosystem. There are some organogermanes which are characterized by confirmed neurotropic activity. Others have positive influence on the blood circulation. Some others are used in anti-cancer therapy. Germanium derivatives, because of their properties that are similar to but not identical to, silica properties, are still in the sphere of immense interest. Numerous hopes are set on their applications, first of all with possibilities of pharmacological use against different diseases, including malignant tumors and AIDS. Generally organogermanium preparations are less toxic than their silicon analogs.

Keywords:

• benzyl germanium derivatives: di-
• tri-
• tetra-
• hexa-
• properties
• determination
• separation
• furylgermanium

Notes

*-LD₅₀ (μ g.mL^{− 1}): MTT and CV.