Chiral Recognition Methods in Analytical Chemistry: Role of the Chiral Ionic Liquids

Abstract

The increasing demand of the chiral compounds in drug and food industries has stimulated the considerable attention towards the chiral recognition and separation methods. For this, a number of chiral selectors have been employed for the recognition of enantiomers. In this context, chiral ionic liquids (CILs) have appeared as cheap and lucrative chiral selectors. The present report enlightens the role of CILs in chiral recognition of the enantiomers using various analytical techniques such as NMR and fluorescence spectroscopy, liquid and gas chromatography and capillary electrophoresis. Due to plethora of reports published in this direction, we have tried to limit our discussion about the literature published in the last decade only.

Keywords:

• Capillary electrophoresis
• chiral ionic liquids
• chiral recognition
• diastereomeric complexes
• enantiodifferentiation
• enantiomers
• fluorescence spectroscopy
• gas chromatography
• high-performance liquid chromatography
• NMR spectroscopy

Acknowledgment

Authors are also thankful to the authorities of Sant Longowal Institute of Engineering and Technology for providing the research facilities.

Disclosure statement

The authors declare no conflicts of interest.

Additional information

Funding

One of the author (Avtar Singh) is thankful to DST, MHRD, Govt of India for providing financial help under INSPIRE Fellowship scheme [IF 140327].