Functionalized Chiral Materials for Use in Chiral Sensors

Abstract

Chirality represents a fundamental attribute within living systems and is a pervasive phenomenon in the natural world. The identification and analysis of chiral materials within natural environments and biological systems hold paramount importance in clinical, chemical, and biological sciences. Within chiral analysis, there is a burgeoning focus on developing chiral sensors exhibiting exceptional selectivity, sensitivity, and stability, marking it as a forefront area of research. In the past decade (2013–2023), approximately 1990 papers concerning the application of various chiral materials in chiral sensors have been published. Biological materials and nanomaterials have important applications in the development of chiral sensors, which accounting for 26.67% and 45.24% of the material-related applications in these sensors, respectively; moreover, the development of chiral nanomaterials is closely related to the development of portable and stable chiral sensors. Natural chiral materials, utilized as selective recognition units, are combined with carriers characterized by good physical and chemical properties through functionalization to form various functional chiral materials, which improve the recognition efficiency of chiral sensors. In this article, from the perspective of biological materials, polymer materials, nanomaterials, and other functional chiral materials, the applications of chiral sensors are summarized and the research prospects of chiral sensors are discussed.

Keywords:

• Chirality
• chiral materials
• biological materials
• nanomaterials
• sensors

Disclosure statement

The authors declare no potential conflict of interest.

Additional information

Funding

The work was supported by Key Laboratory of Tropical Fruits and Vegetables Quality and Safety for State Market Regulation (No. KF-2023006), the Science and Technology Project of Guangxi (No. Guike AD19110059), Guilin University of Technology (No. GUTQDJJ2016024), and the New Technology of Food Safety Testing, Guilin University of Technology.